114772-53-1

  • Product Name:4'-Methyl-2-cyanobiphenyl
  • Molecular Formula:C14H11N
  • Purity:99%
  • Molecular Weight:193.248
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Product Details;

CasNo: 114772-53-1

Molecular Formula: C14H11N

Appearance: white crystalline powder

Quality products make an important contribution to long-term revenue and profitability. We supply Pharmaceutical Intermediates 4'-Methyl-2-cyanobiphenyl 114772-53-1 Crystalline Powder for You.

1.What is the 4'-Methyl-2-cyanobiphenyl ?

4''-Methylbiphenyl-2-carbonitrile is an intermediate in the synthesis of glycogen synthase kinase-3 inhibitors with a selective sting for glycogen synthase kinase 3α. It is a chemical compound that belongs to the family of biphenyls, which are organic compounds consisting of two benzene rings connected by a single bond.

2-Chlorobenzonitrile
873-32-5

2-Chlorobenzonitrile

4-tolylmagnesium chloride
696-61-7

4-tolylmagnesium chloride

(4,4'-dimethyl-1,1'-biphenyl)
613-33-2

(4,4'-dimethyl-1,1'-biphenyl)

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
Conditions Yield
With triisopropyl phosphite; Ni(acac); methylmagnesium chloride; zinc(II) chloride; In tetrahydrofuran; water; at 55 ℃;
82%
4-tolyl iodide
624-31-7

4-tolyl iodide

o-cyanobromobenzene
2042-37-7

o-cyanobromobenzene

(4,4'-dimethyl-1,1'-biphenyl)
613-33-2

(4,4'-dimethyl-1,1'-biphenyl)

2-Cyano-4'-methylbiphenyl
114772-53-1

2-Cyano-4'-methylbiphenyl

Conditions
Conditions Yield
With tetrabutylammomium bromide; N-ethyl-N,N-diisopropylamine; palladium diacetate; In xylene; at 130 ℃; for 63h;
33%
14 % Chromat.

2.What is the CAS number for 4'-Methyl-2-cyanobiphenyl ?

The CAS number of 4'-Methyl-2-cyanobiphenyl is 114772-53-1.

More information of 4'-Methyl-2-cyanobiphenyl 114772-53-1 are:

CAS Number

114772-53-1

Density

1.09 g/cm3

Melting Point

49 °C

Boiling Point

356.8 °C at 760 mmHg

Flash Point

170.4 °C

Vapor Pressure

0.014Pa at 20℃

HS CODE

27075000

PSA

23.79000

LogP

3.53368

3.What are another words for 4'-Methyl-2-cyanobiphenyl ?

Synonyms for 4'-Methyl-2-cyanobiphenyl 114772-53-1:2'-Cyano-4-methylbiphenyl;4-Methyl-2'-cyanobiphenyl;2-(4-Methylphenyl)benzonitrile;2-(p-Tolyl)benzonitrile;2-Cyano-4'-methyl-1,1'-biphenyl;2-Cyano-4'-methylbiphenyl;OTBN(O-Tolybenzenitrile);

4.What is the molecular formula of 4'-Methyl-2-cyanobiphenyl?

The chemical formula of  4'-Methyl-2-cyanobiphenyl is C14H11N which containing 14 Carbon atoms,11 Hydrogen atoms and 1 Nitrogen atoms,and the molecular weight of  4'-Methyl-2-cyanobiphenyl is 193.248.

5.What is 4'-Methyl-2-cyanobiphenyl (114772-53-1) used for?

4'-Methyl-2-cyanobiphenyl is key intermediate for many marketed antihypertensive drugs such as Condesartan, Losartan, Irbesartan and Valsartan. It is commonly used as a liquid crystal material in electronic displays, such as those found in televisions, computer monitors, and mobile phones. However, 4'-Methyl-2-cyanobiphenyl has been identified as a potential environmental pollutant and has been found to be toxic to aquatic organisms. As a result, its use and disposal are regulated in many countries.

Isomeric SMILES: CC1=CC=C(C=C1)C2=CC=CC=C2C#N  
InChIKey: ZGQVZLSNEBEHFN-UHFFFAOYSA-N  
InChI: InChI=1S/C14H11N/c1-11-6-8-12(9-7-11)14-5-3-2-4-13(14)10-15/h2-9H,1H3  

Relevant articles related to 4'-Methyl-2-cyanobiphenyl:

Article

Source

Design and synthesis of new tetrazolyl- and carboxy-biphenylylmethyl- quinazolin-4-one derivatives as angiotensin II AT1 receptor antagonists

Ismail, Mohamed A. H.,Barker, Stewart,Abou El Ella, Dalal A.,Abouzid, Khaled A. M.,Toubar, Rabab A.,Todd, Matthew H.

, p. 1526 - 1535 (2006)

Quantum mechanical study of the structure and spectroscopic (FT-IR, FT-Raman, 13C, 1H and UV), first order hyperpolarizabilities, NBO and TD-DFT analysis of the 4-methyl-2-cyanobiphenyl Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy Volume 78, Issue 2, February 2011, Pages 590-600

6.Buy Pharmaceutical Intermediates 4'-Methyl-2-cyanobiphenyl 114772-53-1 Crystalline Powder.

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